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human, Cynomolgus/ Rhesus macaque, rat, mouse interferon, lambda 1(IFNL1) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to IL29/IFNL1 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse interferon, lambda 1 (IFNL1) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
IFNL1 (Interferon Lambda 1) is a Protein Coding gene. Diseases associated with IFNL1 include Cd4/Cd8 T-Cell Ratio and Psoriasis 12. Among its related pathways are Toll-Like receptor Signaling Pathways and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and interleukin-28 receptor binding. An important paralog of this gene is IFNL3.
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T78381-Ag-1 | interferon, lambda 1 (IFNL1) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T78381-Ab-1 | Anti-IFNL1 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T78381-Ab-2 | Anti-IFNL1 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T78381-Ag-1 | interferon, lambda 1 (IFNL1) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T78381-Ab-1 | Anti-IFNL1 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T78381-Ab-2 | Anti-IFNL1 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T78381-Ag-1 | interferon, lambda 1 (IFNL1) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T78381-Ab-1 | Anti-IFNL1 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T78381-Ab-2 | Anti-IFNL1 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T78381-Ag-1 | interferon, lambda 1 (IFNL1) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T78381-Ab-1 | Anti-IFNL1 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T78381-Ab-2 | Anti-IFNL1 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | IFNL1 |
| Full name | interferon, lambda 1 |
| Gene ID | 282618 |
| Gene Name | IFNL1 |
| Gene Alias | IL-29, IL29 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
| Cat No. | GM-Tg-hg-T78381-Ag-1, GM-Tg-rg-T78381-Ag-1, GM-Tg-mg-T78381-Ag-1, GM-Tg-cynog-T78381-Ag-1 |
| Products Name | interferon, lambda 1 (IFNL1) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse interferon, lambda 1 (IFNL1) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T78381-Ab-1, GM-Tg-hg-T78381-Ab-2, GM-Tg-rg-T78381-Ab-1, GM-Tg-rg-T78381-Ab-2, GM-Tg-mg-T78381-Ab-1, GM-Tg-mg-T78381-Ab-2, GM-Tg-cynog-T78381-Ab-1, GM-Tg-cynog-T78381-Ab-2 |
| Products Name | Anti-IL29/IFNL1 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL29 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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