human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 8B(WNT8B) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 8B (WNT8B) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. The Wnt family member 8B (Wnt8B) is one of the canonical Wnt ligands implicated in oncogenesis, several developmental processes, including regulation of cell fate and patterning during embryogenesis, and other pathophysiological processes. Wnt8B expression was detected in embryoid body derived from ES cells, hepatocyte progenitors derived from ES cells, and fetal brain. It also expressed in several tumors such as gastric cancer, pancreatic cancer, colorectal cancer, breast cancer, and embryonal tumors.


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity		SizePrice
GM-Tg-hg-SE1385-Ag-1wingless-type MMTV integration site family, member 8B (WNT8B) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-SE1385-Ab-1Anti-WNT8B monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-SE1385-Ab-2Anti-WNT8B monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1385-Ag-1wingless-type MMTV integration site family, member 8B (WNT8B)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1385-Ab-1Anti-WNT8B monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1385-Ab-2Anti-WNT8B monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1385-Ag-1wingless-type MMTV integration site family, member 8B (WNT8B)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1385-Ab-1Anti-WNT8B monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1385-Ab-2Anti-WNT8B monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1385-Ag-1wingless-type MMTV integration site family, member 8B (WNT8B)Cynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1385-Ab-1Anti-WNT8B monoclonal antibodyCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1385-Ab-2Anti-WNT8B monoclonal antibodyCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameWNT8B
Full namewingless-type MMTV integration site family, member 8B
Gene ID7479
Gene NameWNT8B
Gene Alias
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-SE1385-Ag-1, GM-Tg-rg-SE1385-Ag-1, GM-Tg-mg-SE1385-Ag-1, GM-Tg-cynog-SE1385-Ag-1
Products Namewingless-type MMTV integration site family, member 8B (WNT8B) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 8B (WNT8B) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-SE1385-Ab-1, GM-Tg-hg-SE1385-Ab-2,
GM-Tg-rg-SE1385-Ab-1, GM-Tg-rg-SE1385-Ab-2,
GM-Tg-mg-SE1385-Ab-1, GM-Tg-mg-SE1385-Ab-2,
GM-Tg-cynog-SE1385-Ab-1, GM-Tg-cynog-SE1385-Ab-2
Products NameAnti-WNT8B monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-WNT8B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.