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human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 27 receptor, alpha(IL27RA) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to IL27R/IL27RA products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 27 receptor, alpha (IL27RA) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Interleukin 27 receptor, alpha is a subunit of the interleukin-27 receptor. IL27RA is its human gene.
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-IO077-Ag-1 | interleukin 27 receptor, alpha (IL27RA) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-IO077-Ab-1 | Anti-IL27RA monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-IO077-Ab-2 | Anti-IL27RA monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-IO077-Ag-1 | interleukin 27 receptor, alpha (IL27RA) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-IO077-Ab-1 | Anti-IL27RA monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-IO077-Ab-2 | Anti-IL27RA monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-IO077-Ag-1 | interleukin 27 receptor, alpha (IL27RA) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-IO077-Ab-1 | Anti-IL27RA monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-IO077-Ab-2 | Anti-IL27RA monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-IO077-Ag-1 | interleukin 27 receptor, alpha (IL27RA) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-IO077-Ab-1 | Anti-IL27RA monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-IO077-Ab-2 | Anti-IL27RA monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | IL27RA |
| Full name | interleukin 27 receptor, alpha |
| Gene ID | 9466 |
| Gene Name | IL27RA |
| Gene Alias | CRL1, IL-27RA, IL27R, TCCR, WSX1, zcytor1 |
| Protein Sub-location | Transmembrane Protein |
Antigen Information
| Cat No. | GM-Tg-hg-IO077-Ag-1, GM-Tg-rg-IO077-Ag-1, GM-Tg-mg-IO077-Ag-1, GM-Tg-cynog-IO077-Ag-1 |
| Products Name | interleukin 27 receptor, alpha (IL27RA) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 27 receptor, alpha (IL27RA) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-IO077-Ab-1, GM-Tg-hg-IO077-Ab-2, GM-Tg-rg-IO077-Ab-1, GM-Tg-rg-IO077-Ab-2, GM-Tg-mg-IO077-Ab-1, GM-Tg-mg-IO077-Ab-2, GM-Tg-cynog-IO077-Ab-1, GM-Tg-cynog-IO077-Ab-2 |
| Products Name | Anti-IL27R/IL27RA monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL27R benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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