Recombinant multi-species HIF1A/ HIF-1A/ HIF-1-alpha protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HIF-1A/HIF1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: HIF-1A, gene name: HIF1A, also named as HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011].
Order information
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Catalog No. | Product Name | Species | Size | Price |
GM-Tg-hg-IP0067-Ag-1 | Human HIF-1A/HIF1A protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-IP0067-Ag-1 | Rat HIF-1A/HIF1A protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-IP0067-Ag-1 | Mouse HIF-1A/HIF1A protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-IP0067-Ag-1 | Cynomolgus/ Rhesus macaque HIF-1A/HIF1A protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-felg-IP0067-Ag-1 | Feline HIF-1A/HIF1A protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cang-IP0067-Ag-1 | Canine HIF-1A/HIF1A protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-IP0067-Ag-1 | Bovine HIF-1A/HIF1A protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-bovg-IP0067-Ag-1 | Equine HIF-1A/HIF1A protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Catalog No. | GM-Tg-hg-IP0067-Ag, GM-Tg-rg-IP0067-Ag, GM-Tg-mg-IP0067-Ag, GM-Tg-cynog-IP0067-Ag, GM-Tg-felg-IP0067-Ag, GM-Tg-cang-IP0067-Ag, GM-Tg-bovg-IP0067-Ag, GM-Tg-equg-IP0067-Ag-1 |
Products Name | HIF-1A/HIF1A protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | HIF-1A |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HIF-1A/HIF1A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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