Adenovirus vector for overexpression: pADV-U6/CMV-promoter/Null reporter

GeneMedi's adenovirus U6 expression vector is inserted with a promoter for human U6 to drive gene knockdown. You can contact Genemedi for your unique reporter including GFP, zsgreen, RFP, mcherry or luciferase.GeneMedi's adenovirus CMV expression vector is inserted with a promoter for cytomegalovirus (CMV) to drive gene overexpression. You can contact Genemedi for your unique reporter including GFP, zsgreen, RFP, mcherry or luciferase.

U6 is a type III RNA polymerase III promoter commonly used for driving small hairpin RNA (shRNA) expression in vector-based RNAi.The CMV promoter is a strong protomer driven broad expression in most tissues.

You can easily produce a recombinant adenovirus (r-AdV) particle in HEK293 or HEK293A cell line in high titer using GeneMedi's adenovirus Vector System including the adenovirus expression plasmids (overexpression, shRNA or Crispr-cas9-gRNA) and the adenovirus genome backbone plasmid.