human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) receptor 9(CCR9) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) receptor 9 (CCR9) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

C-C chemokine receptor type 9 is a protein that in humans is encoded by the CCR9 gene. CCR9 has also recently been designated CDw199 (cluster of differentiation w199). The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammatory conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in thymocyte recruitment and development that may permit functional specialization of immune responses in different segments of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity		SizePrice
GM-Tg-hg-T97873-Ag-1chemokine (C-C motif) receptor 9 (CCR9) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T97873-Ab-1Anti-CCR9 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-T97873-Ab-2Anti-CCR9 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T97873-Ag-1chemokine (C-C motif) receptor 9 (CCR9)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T97873-Ab-1Anti-CCR9 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T97873-Ab-2Anti-CCR9 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T97873-Ag-1chemokine (C-C motif) receptor 9 (CCR9)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T97873-Ab-1Anti-CCR9 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T97873-Ab-2Anti-CCR9 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T97873-Ag-1chemokine (C-C motif) receptor 9 (CCR9)Cynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T97873-Ab-1Anti-CCR9 monoclonal antibodyCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T97873-Ab-2Anti-CCR9 monoclonal antibodyCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameCCR9
Full namechemokine (C-C motif) receptor 9
Gene ID10803
Gene NameCCR9
Gene AliasCC-CKR-9, CDw199, GPR-9-6, GPR28
Protein Sub-locationTransmembrane Protein

Antigen Information

Cat No.GM-Tg-hg-T97873-Ag-1, GM-Tg-rg-T97873-Ag-1, GM-Tg-mg-T97873-Ag-1, GM-Tg-cynog-T97873-Ag-1
Products Namechemokine (C-C motif) receptor 9 (CCR9) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) receptor 9 (CCR9) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-T97873-Ab-1, GM-Tg-hg-T97873-Ab-2,
GM-Tg-rg-T97873-Ab-1, GM-Tg-rg-T97873-Ab-2,
GM-Tg-mg-T97873-Ab-1, GM-Tg-mg-T97873-Ab-2,
GM-Tg-cynog-T97873-Ab-1, GM-Tg-cynog-T97873-Ab-2
Products NameAnti-CCR9 monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CCR9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.