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human, Cynomolgus/ Rhesus macaque, rat, mouse SMAD family member 7(SMAD7) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to SMAD7/SMAD7 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse SMAD family member 7 (SMAD7) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Mothers against decapentaplegic homolog 7 or SMAD7 is a protein that in humans is encoded by the SMAD7 gene.
SMAD7 is a protein that, as its name describes, is a homolog of the Drosophila gene: "Mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the TGFβ superfamily of ligands. Like many other TGFβ family members, SMAD7 is involved in cell signalling. It is a TGFβ type 1 receptor antagonist. It blocks TGFβ1 and activin associating with the receptor, blocking access to SMAD2. It is an inhibitory SMAD (I-SMAD) and is enhanced by SMURF2.
Smad7 enhances muscle differentiation.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T94695-Ag-1 | SMAD family member 7 (SMAD7) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T94695-Ab-1 | Anti-SMAD7 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T94695-Ab-2 | Anti-SMAD7 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T94695-Ag-1 | SMAD family member 7 (SMAD7) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T94695-Ab-1 | Anti-SMAD7 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T94695-Ab-2 | Anti-SMAD7 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T94695-Ag-1 | SMAD family member 7 (SMAD7) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T94695-Ab-1 | Anti-SMAD7 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T94695-Ab-2 | Anti-SMAD7 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T94695-Ag-1 | SMAD family member 7 (SMAD7) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T94695-Ab-1 | Anti-SMAD7 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T94695-Ab-2 | Anti-SMAD7 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | SMAD7 |
| Full name | SMAD family member 7 |
| Gene ID | 4092 |
| Gene Name | SMAD7 |
| Gene Alias | CRCS3, MADH7, MADH8 |
| Protein Sub-location | Introcelluar Protein |
Antigen Information
| Cat No. | GM-Tg-hg-T94695-Ag-1, GM-Tg-rg-T94695-Ag-1, GM-Tg-mg-T94695-Ag-1, GM-Tg-cynog-T94695-Ag-1 |
| Products Name | SMAD family member 7 (SMAD7) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse SMAD family member 7 (SMAD7) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T94695-Ab-1, GM-Tg-hg-T94695-Ab-2, GM-Tg-rg-T94695-Ab-1, GM-Tg-rg-T94695-Ab-2, GM-Tg-mg-T94695-Ab-1, GM-Tg-mg-T94695-Ab-2, GM-Tg-cynog-T94695-Ab-1, GM-Tg-cynog-T94695-Ab-2 |
| Products Name | Anti-SMAD7 monoclonal antibody |
| Format | mab |
| Category of antibody | Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SMAD7 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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