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human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) ligand 21(CCL21) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to CCL21/CCL21 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) ligand 21 (CCL21) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Chemokine (C-C motif) ligand 21 (CCL21) is a small cytokine belonging to the CC chemokine family. This chemokine is also known as 6Ckine (because it has six conserved cysteine residues instead of the four cysteines typical to chemokines), exodus-2, and secondary lymphoid-tissue chemokine (SLC). The gene for CCL21 is located on human chromosome 9. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7.
In human lymph nodes, the fibroblastic reticular cells (FRCs) express CCL21 as a chemoattractant to guide naive, CCR7 expressing T cells to the T cell zone.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T93237-Ag-1 | chemokine (C-C motif) ligand 21 (CCL21) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T93237-Ab-1 | Anti-CCL21 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T93237-Ab-2 | Anti-CCL21 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T93237-Ag-1 | chemokine (C-C motif) ligand 21 (CCL21) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T93237-Ab-1 | Anti-CCL21 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T93237-Ab-2 | Anti-CCL21 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T93237-Ag-1 | chemokine (C-C motif) ligand 21 (CCL21) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T93237-Ab-1 | Anti-CCL21 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T93237-Ab-2 | Anti-CCL21 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T93237-Ag-1 | chemokine (C-C motif) ligand 21 (CCL21) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T93237-Ab-1 | Anti-CCL21 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T93237-Ab-2 | Anti-CCL21 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | CCL21 |
| Full name | chemokine (C-C motif) ligand 21 |
| Gene ID | 6366 |
| Gene Name | CCL21 |
| Gene Alias | 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
| Cat No. | GM-Tg-hg-T93237-Ag-1, GM-Tg-rg-T93237-Ag-1, GM-Tg-mg-T93237-Ag-1, GM-Tg-cynog-T93237-Ag-1 |
| Products Name | chemokine (C-C motif) ligand 21 (CCL21) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) ligand 21 (CCL21) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T93237-Ab-1, GM-Tg-hg-T93237-Ab-2, GM-Tg-rg-T93237-Ab-1, GM-Tg-rg-T93237-Ab-2, GM-Tg-mg-T93237-Ab-1, GM-Tg-mg-T93237-Ab-2, GM-Tg-cynog-T93237-Ab-1, GM-Tg-cynog-T93237-Ab-2 |
| Products Name | Anti-CCL21 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL21 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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