Products
human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor receptor 3(FGFR3) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to FGFR3/FGFR3 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor receptor 3 (FGFR3) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Fibroblast growth factor receptor 3 is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster of differentiation 333). The gene, which is located on chromosome 4, location p16.3, is expressed in tissues such as the cartilage, brain, intestine, and kidneys.
The FGFR3 gene produces various forms of the FGFR3 protein; the location varies depending on the isoform of the FGFR3 protein. Since the different forms are found within different tissues the protein is responsible for multiple growth factor interactions. Gain of function mutations in FGFR3 inhibits chondrocyte proliferation and underlies achondroplasia and hypochondroplasia.
Order information
* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry
| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T91331-Ag-1 | fibroblast growth factor receptor 3 (FGFR3) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T91331-Ab-1 | Anti-FGFR3 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T91331-Ab-2 | Anti-FGFR3 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T91331-Ag-1 | fibroblast growth factor receptor 3 (FGFR3) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T91331-Ab-1 | Anti-FGFR3 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T91331-Ab-2 | Anti-FGFR3 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T91331-Ag-1 | fibroblast growth factor receptor 3 (FGFR3) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T91331-Ab-1 | Anti-FGFR3 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T91331-Ab-2 | Anti-FGFR3 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T91331-Ag-1 | fibroblast growth factor receptor 3 (FGFR3) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T91331-Ab-1 | Anti-FGFR3 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T91331-Ab-2 | Anti-FGFR3 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | FGFR3 |
| Full name | fibroblast growth factor receptor 3 |
| Gene ID | 2261 |
| Gene Name | FGFR3 |
| Gene Alias | ACH, CD333, CEK2, HSFGFR3EX, JTK4 |
| Protein Sub-location | Transmembrane Protein |
Antigen Information
| Cat No. | GM-Tg-hg-T91331-Ag-1, GM-Tg-rg-T91331-Ag-1, GM-Tg-mg-T91331-Ag-1, GM-Tg-cynog-T91331-Ag-1 |
| Products Name | fibroblast growth factor receptor 3 (FGFR3) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor receptor 3 (FGFR3) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T91331-Ab-1, GM-Tg-hg-T91331-Ab-2, GM-Tg-rg-T91331-Ab-1, GM-Tg-rg-T91331-Ab-2, GM-Tg-mg-T91331-Ab-1, GM-Tg-mg-T91331-Ab-2, GM-Tg-cynog-T91331-Ab-1, GM-Tg-cynog-T91331-Ab-2 |
| Products Name | Anti-FGFR3 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FGFR3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Facebook
LinkedIn
Twitter
