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human, Cynomolgus/ Rhesus macaque, rat, mouse leptin(LEP) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to LEP/LEP products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse leptin (LEP) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Leptin (from Greek λεπτός leptos, "thin") is a hormone predominantly made by adipose cells and enterocytes in the small intestine that helps to regulate energy balance by inhibiting hunger, which in turn diminishes fat storage in adipocytes. Leptin acts on cell receptors in the arcuate and ventromedial nuclei, as well as other parts of the hypothalamus and dopaminergic neurons of the ventral tegmental area, consequently mediating feeding.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T79485-Ag-1 | leptin (LEP) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T79485-Ab-1 | Anti-LEP monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T79485-Ab-2 | Anti-LEP monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T79485-Ag-1 | leptin (LEP) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T79485-Ab-1 | Anti-LEP monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T79485-Ab-2 | Anti-LEP monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T79485-Ag-1 | leptin (LEP) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T79485-Ab-1 | Anti-LEP monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T79485-Ab-2 | Anti-LEP monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T79485-Ag-1 | leptin (LEP) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T79485-Ab-1 | Anti-LEP monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T79485-Ab-2 | Anti-LEP monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | LEP |
| Full name | leptin |
| Gene ID | 3952 |
| Gene Name | LEP |
| Gene Alias | LEPD, OB, OBS |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
| Cat No. | GM-Tg-hg-T79485-Ag-1, GM-Tg-rg-T79485-Ag-1, GM-Tg-mg-T79485-Ag-1, GM-Tg-cynog-T79485-Ag-1 |
| Products Name | leptin (LEP) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse leptin (LEP) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T79485-Ab-1, GM-Tg-hg-T79485-Ab-2, GM-Tg-rg-T79485-Ab-1, GM-Tg-rg-T79485-Ab-2, GM-Tg-mg-T79485-Ab-1, GM-Tg-mg-T79485-Ab-2, GM-Tg-cynog-T79485-Ab-1, GM-Tg-cynog-T79485-Ab-2 |
| Products Name | Anti-LEP monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-LEP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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