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human, Cynomolgus/ Rhesus macaque, rat, mouse glial cell derived neurotrophic factor(GDNF) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to GDNF/GDNF products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse glial cell derived neurotrophic factor (GDNF) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Glial cell-derived neurotrophic factor (GDNF) is a protein that, in humans, is encoded by the GDNF gene. GDNF is a small protein that potently promotes the survival of many types of neurons. It signals through GFRα receptors, particularly GFRα1. It is also responsible for the determination of spermatogonia into primary spermatocytes i.e. It is received by RET and by forming gradient with SCF it divides the spermatogonia into two cells. As the result there is retention of spermatogonia and formation of spermatocyte.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T79160-Ag-1 | glial cell derived neurotrophic factor (GDNF) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T79160-Ab-1 | Anti-GDNF monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T79160-Ab-2 | Anti-GDNF monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T79160-Ag-1 | glial cell derived neurotrophic factor (GDNF) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T79160-Ab-1 | Anti-GDNF monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T79160-Ab-2 | Anti-GDNF monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T79160-Ag-1 | glial cell derived neurotrophic factor (GDNF) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T79160-Ab-1 | Anti-GDNF monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T79160-Ab-2 | Anti-GDNF monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T79160-Ag-1 | glial cell derived neurotrophic factor (GDNF) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T79160-Ab-1 | Anti-GDNF monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T79160-Ab-2 | Anti-GDNF monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | GDNF |
| Full name | glial cell derived neurotrophic factor |
| Gene ID | 2668 |
| Gene Name | GDNF |
| Gene Alias | ATF, ATF1, ATF2, HFB1-GDNF, HSCR3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
| Cat No. | GM-Tg-hg-T79160-Ag-1, GM-Tg-rg-T79160-Ag-1, GM-Tg-mg-T79160-Ag-1, GM-Tg-cynog-T79160-Ag-1 |
| Products Name | glial cell derived neurotrophic factor (GDNF) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse glial cell derived neurotrophic factor (GDNF) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T79160-Ab-1, GM-Tg-hg-T79160-Ab-2, GM-Tg-rg-T79160-Ab-1, GM-Tg-rg-T79160-Ab-2, GM-Tg-mg-T79160-Ab-1, GM-Tg-mg-T79160-Ab-2, GM-Tg-cynog-T79160-Ab-1, GM-Tg-cynog-T79160-Ab-2 |
| Products Name | Anti-GDNF monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GDNF benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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