human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 7A(WNT7A) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 7A (WNT7A) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Protein Wnt-7a is a protein that in humans is encoded by the WNT7A gene.
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein showing 99% amino acid identity to the mouse Wnt7A protein. This gene not only guides the development of the anterior-posterior axis in the female reproductive tract but also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. It is also responsive to changes in the levels of sex steroid hormone in the female reproductive tract. Decreased expression of this gene in human uterine leiomyoma is found to be inversely associated with the expression of estrogen receptor alpha.
Order information
* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry
Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
GM-Tg-hg-T73908-Ag-1 | wingless-type MMTV integration site family, member 7A (WNT7A) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-hg-T73908-Ab-1 | Anti-WNT7A monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-hg-T73908-Ab-2 | Anti-WNT7A monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T73908-Ag-1 | wingless-type MMTV integration site family, member 7A (WNT7A) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T73908-Ab-1 | Anti-WNT7A monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T73908-Ab-2 | Anti-WNT7A monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T73908-Ag-1 | wingless-type MMTV integration site family, member 7A (WNT7A) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T73908-Ab-1 | Anti-WNT7A monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T73908-Ab-2 | Anti-WNT7A monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T73908-Ag-1 | wingless-type MMTV integration site family, member 7A (WNT7A) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T73908-Ab-1 | Anti-WNT7A monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T73908-Ab-2 | Anti-WNT7A monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Target Information
Target Name | WNT7A |
Full name | wingless-type MMTV integration site family, member 7A |
Gene ID | 7476 |
Gene Name | WNT7A |
Gene Alias | |
Protein Sub-location | Transmembrane Protein |
Antigen Information
Cat No. | GM-Tg-hg-T73908-Ag-1, GM-Tg-rg-T73908-Ag-1, GM-Tg-mg-T73908-Ag-1, GM-Tg-cynog-T73908-Ag-1 |
Products Name | wingless-type MMTV integration site family, member 7A (WNT7A) protein |
Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
Tag | His |
Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse wingless-type MMTV integration site family, member 7A (WNT7A) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
Catalog No. | GM-Tg-hg-T73908-Ab-1, GM-Tg-hg-T73908-Ab-2, GM-Tg-rg-T73908-Ab-1, GM-Tg-rg-T73908-Ab-2, GM-Tg-mg-T73908-Ab-1, GM-Tg-mg-T73908-Ab-2, GM-Tg-cynog-T73908-Ab-1, GM-Tg-cynog-T73908-Ab-2 |
Products Name | Anti-WNT7A monoclonal antibody |
Format | mab |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
Derivation (species) | Mouse |
Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-WNT7A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |