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human, Cynomolgus/ Rhesus macaque, rat, mouse SMAD family member 3(SMAD3) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to SMAD3/SMAD3 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse SMAD family member 3 (SMAD3) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene.
SMAD3 is a member of the SMAD family of proteins. It acts as a mediator of the signals initiated by the transforming growth factor beta (TGF-β) superfamily of cytokines, which regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T35445-Ag-1 | SMAD family member 3 (SMAD3) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T35445-Ab-1 | Anti-SMAD3 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T35445-Ab-2 | Anti-SMAD3 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T35445-Ag-1 | SMAD family member 3 (SMAD3) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T35445-Ab-1 | Anti-SMAD3 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T35445-Ab-2 | Anti-SMAD3 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T35445-Ag-1 | SMAD family member 3 (SMAD3) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T35445-Ab-1 | Anti-SMAD3 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T35445-Ab-2 | Anti-SMAD3 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T35445-Ag-1 | SMAD family member 3 (SMAD3) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T35445-Ab-1 | Anti-SMAD3 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T35445-Ab-2 | Anti-SMAD3 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | SMAD3 |
| Full name | SMAD family member 3 |
| Gene ID | 4088 |
| Gene Name | SMAD3 |
| Gene Alias | HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3 |
| Protein Sub-location | Introcelluar Protein |
Antigen Information
| Cat No. | GM-Tg-hg-T35445-Ag-1, GM-Tg-rg-T35445-Ag-1, GM-Tg-mg-T35445-Ag-1, GM-Tg-cynog-T35445-Ag-1 |
| Products Name | SMAD family member 3 (SMAD3) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse SMAD family member 3 (SMAD3) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T35445-Ab-1, GM-Tg-hg-T35445-Ab-2, GM-Tg-rg-T35445-Ab-1, GM-Tg-rg-T35445-Ab-2, GM-Tg-mg-T35445-Ab-1, GM-Tg-mg-T35445-Ab-2, GM-Tg-cynog-T35445-Ab-1, GM-Tg-cynog-T35445-Ab-2 |
| Products Name | Anti-SMAD3 monoclonal antibody |
| Format | mab |
| Category of antibody | Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SMAD3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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