human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) ligand 23(CCL23) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) ligand 23 (CCL23) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family that is also known as Macrophage inflammatory protein 3 (MIP-3) and Myeloid progenitor inhibitory factor 1 (MPIF-1). CCL23 is predominantly expressed in lung and liver tissue, but is also found in bone marrow and placenta. It is also expressed in some cell lines of myeloid origin. CCL23 is highly chemotactic for resting T cells and monocytes and slightly chemotactic for neutrophils. It has also been attributed to an inhibitory activity on hematopoietic progenitor cells. The gene for CCL23 is located on human chromosome 17 in a locus containing several other CC chemokines. CCL23 is a ligand for the chemokine receptor CCR1.
Order information
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Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
GM-Tg-hg-T23934-Ag-1 | chemokine (C-C motif) ligand 23 (CCL23) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-hg-T23934-Ab-1 | Anti-CCL23 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-hg-T23934-Ab-2 | Anti-CCL23 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T23934-Ag-1 | chemokine (C-C motif) ligand 23 (CCL23) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T23934-Ab-1 | Anti-CCL23 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-rg-T23934-Ab-2 | Anti-CCL23 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T23934-Ag-1 | chemokine (C-C motif) ligand 23 (CCL23) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T23934-Ab-1 | Anti-CCL23 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-mg-T23934-Ab-2 | Anti-CCL23 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T23934-Ag-1 | chemokine (C-C motif) ligand 23 (CCL23) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T23934-Ab-1 | Anti-CCL23 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
GM-Tg-cynog-T23934-Ab-2 | Anti-CCL23 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
Shipping Cost: | 760.00 |
Description
Target Information
Target Name | CCL23 |
Full name | chemokine (C-C motif) ligand 23 |
Gene ID | 6368 |
Gene Name | CCL23 |
Gene Alias | CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23, hmrp-2a |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
Cat No. | GM-Tg-hg-T23934-Ag-1, GM-Tg-rg-T23934-Ag-1, GM-Tg-mg-T23934-Ag-1, GM-Tg-cynog-T23934-Ag-1 |
Products Name | chemokine (C-C motif) ligand 23 (CCL23) protein |
Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
Tag | His |
Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) ligand 23 (CCL23) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
Catalog No. | GM-Tg-hg-T23934-Ab-1, GM-Tg-hg-T23934-Ab-2, GM-Tg-rg-T23934-Ab-1, GM-Tg-rg-T23934-Ab-2, GM-Tg-mg-T23934-Ab-1, GM-Tg-mg-T23934-Ab-2, GM-Tg-cynog-T23934-Ab-1, GM-Tg-cynog-T23934-Ab-2 |
Products Name | Anti-CCL23 monoclonal antibody |
Format | mab |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
Derivation (species) | Mouse |
Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-CCL23 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |