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human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 10 receptor, beta(IL10RB) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to IL10RB/IL10RB products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 10 receptor, beta (IL10RB) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor. IL10RB is its human gene.
IL10RB has also recently been designated CDW210B (cluster of differentiation W210B).
The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFNAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T14557-Ag-1 | interleukin 10 receptor, beta (IL10RB) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T14557-Ab-1 | Anti-IL10RB monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T14557-Ab-2 | Anti-IL10RB monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T14557-Ag-1 | interleukin 10 receptor, beta (IL10RB) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T14557-Ab-1 | Anti-IL10RB monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T14557-Ab-2 | Anti-IL10RB monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T14557-Ag-1 | interleukin 10 receptor, beta (IL10RB) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T14557-Ab-1 | Anti-IL10RB monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T14557-Ab-2 | Anti-IL10RB monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T14557-Ag-1 | interleukin 10 receptor, beta (IL10RB) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T14557-Ab-1 | Anti-IL10RB monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T14557-Ab-2 | Anti-IL10RB monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | IL10RB |
| Full name | interleukin 10 receptor, beta |
| Gene ID | 3588 |
| Gene Name | IL10RB |
| Gene Alias | CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2 |
| Protein Sub-location | Transmembrane Protein |
Antigen Information
| Cat No. | GM-Tg-hg-T14557-Ag-1, GM-Tg-rg-T14557-Ag-1, GM-Tg-mg-T14557-Ag-1, GM-Tg-cynog-T14557-Ag-1 |
| Products Name | interleukin 10 receptor, beta (IL10RB) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 10 receptor, beta (IL10RB) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T14557-Ab-1, GM-Tg-hg-T14557-Ab-2, GM-Tg-rg-T14557-Ab-1, GM-Tg-rg-T14557-Ab-2, GM-Tg-mg-T14557-Ab-1, GM-Tg-mg-T14557-Ab-2, GM-Tg-cynog-T14557-Ab-1, GM-Tg-cynog-T14557-Ab-2 |
| Products Name | Anti-IL10RB monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL10RB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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