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human, Cynomolgus/ Rhesus macaque, rat, mouse IL-1 R6(IL1RL2) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to IL1RL2/IL1RL2 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse IL-1 R6 (IL1RL2) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
IL-1Rrp2 is also known as IL-1R6. It is a transmembrane protein belonging to the IL-1 receptor family. It is a ligand binding subunit that associates with IL-1RAcP to form a functional receptor complex for IL-1F6, IL-1F8, and IL-1F9. It plays key roles in the activation and amplification of the immune response. Improper receptor signaling has been associated with chronic and acute inflammatory responses and diseases such as rheumatoid arthritis, psoriasis, and lupus erythematosus.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T10988-Ag-1 | IL-1 R6 (IL1RL2) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T10988-Ab-1 | Anti-IL1RL2 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T10988-Ab-2 | Anti-IL1RL2 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T10988-Ag-1 | IL-1 R6 (IL1RL2) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T10988-Ab-1 | Anti-IL1RL2 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T10988-Ab-2 | Anti-IL1RL2 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T10988-Ag-1 | IL-1 R6 (IL1RL2) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T10988-Ab-1 | Anti-IL1RL2 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T10988-Ab-2 | Anti-IL1RL2 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T10988-Ag-1 | IL-1 R6 (IL1RL2) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T10988-Ab-1 | Anti-IL1RL2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T10988-Ab-2 | Anti-IL1RL2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | IL1RL2 |
| Full name | IL-1 R6 |
| Gene ID | 8808 |
| Gene Name | IL1RL2 |
| Gene Alias | IL-1Rrp2, IL-36R, IL1R-rp2, IL1RRP2 |
| Protein Sub-location | Transmembrane Protein |
Antigen Information
| Cat No. | GM-Tg-hg-T10988-Ag-1, GM-Tg-rg-T10988-Ag-1, GM-Tg-mg-T10988-Ag-1, GM-Tg-cynog-T10988-Ag-1 |
| Products Name | IL-1 R6 (IL1RL2) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse IL-1 R6 (IL1RL2) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T10988-Ab-1, GM-Tg-hg-T10988-Ab-2, GM-Tg-rg-T10988-Ab-1, GM-Tg-rg-T10988-Ab-2, GM-Tg-mg-T10988-Ab-1, GM-Tg-mg-T10988-Ab-2, GM-Tg-cynog-T10988-Ab-1, GM-Tg-cynog-T10988-Ab-2 |
| Products Name | Anti-IL1RL2 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL1RL2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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