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human, Cynomolgus/ Rhesus macaque, rat, mouse platelet-derived growth factor alpha polypeptide(PDGFA) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to PDGFA/PDGFA products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse platelet-derived growth factor alpha polypeptide (PDGFA) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene.
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T06869-Ag-1 | platelet-derived growth factor alpha polypeptide (PDGFA) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T06869-Ab-1 | Anti-PDGFA monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T06869-Ab-2 | Anti-PDGFA monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T06869-Ag-1 | platelet-derived growth factor alpha polypeptide (PDGFA) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T06869-Ab-1 | Anti-PDGFA monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T06869-Ab-2 | Anti-PDGFA monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T06869-Ag-1 | platelet-derived growth factor alpha polypeptide (PDGFA) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T06869-Ab-1 | Anti-PDGFA monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T06869-Ab-2 | Anti-PDGFA monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T06869-Ag-1 | platelet-derived growth factor alpha polypeptide (PDGFA) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T06869-Ab-1 | Anti-PDGFA monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T06869-Ab-2 | Anti-PDGFA monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | PDGFA |
| Full name | platelet-derived growth factor alpha polypeptide |
| Gene ID | 5154 |
| Gene Name | PDGFA |
| Gene Alias | PDGF-A, PDGF1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
| Cat No. | GM-Tg-hg-T06869-Ag-1, GM-Tg-rg-T06869-Ag-1, GM-Tg-mg-T06869-Ag-1, GM-Tg-cynog-T06869-Ag-1 |
| Products Name | platelet-derived growth factor alpha polypeptide (PDGFA) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse platelet-derived growth factor alpha polypeptide (PDGFA) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T06869-Ab-1, GM-Tg-hg-T06869-Ab-2, GM-Tg-rg-T06869-Ab-1, GM-Tg-rg-T06869-Ab-2, GM-Tg-mg-T06869-Ab-1, GM-Tg-mg-T06869-Ab-2, GM-Tg-cynog-T06869-Ab-1, GM-Tg-cynog-T06869-Ab-2 |
| Products Name | Anti-PDGFA monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PDGFA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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