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human, Cynomolgus/ Rhesus macaque, rat, mouse interferon (alpha, beta and omega) receptor 2(IFNAR2) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to IFNAR2/IFNAR2 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse interferon (alpha, beta and omega) receptor 2 (IFNAR2) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Interferon-alpha/beta receptor beta chain is a protein that in humans is encoded by the IFNAR2 gene.
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-T06421-Ag-1 | interferon (alpha, beta and omega) receptor 2 (IFNAR2) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T06421-Ab-1 | Anti-IFNAR2 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-T06421-Ab-2 | Anti-IFNAR2 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T06421-Ag-1 | interferon (alpha, beta and omega) receptor 2 (IFNAR2) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T06421-Ab-1 | Anti-IFNAR2 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T06421-Ab-2 | Anti-IFNAR2 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T06421-Ag-1 | interferon (alpha, beta and omega) receptor 2 (IFNAR2) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T06421-Ab-1 | Anti-IFNAR2 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T06421-Ab-2 | Anti-IFNAR2 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T06421-Ag-1 | interferon (alpha, beta and omega) receptor 2 (IFNAR2) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T06421-Ab-1 | Anti-IFNAR2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T06421-Ab-2 | Anti-IFNAR2 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | IFNAR2 |
| Full name | interferon (alpha, beta and omega) receptor 2 |
| Gene ID | 3455 |
| Gene Name | IFNAR2 |
| Gene Alias | IFN-R, IFN-alpha-REC, IFNABR, IFNARB, IMD45 |
| Protein Sub-location | Transmembrane Protein |
Antigen Information
| Cat No. | GM-Tg-hg-T06421-Ag-1, GM-Tg-rg-T06421-Ag-1, GM-Tg-mg-T06421-Ag-1, GM-Tg-cynog-T06421-Ag-1 |
| Products Name | interferon (alpha, beta and omega) receptor 2 (IFNAR2) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse interferon (alpha, beta and omega) receptor 2 (IFNAR2) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-T06421-Ab-1, GM-Tg-hg-T06421-Ab-2, GM-Tg-rg-T06421-Ab-1, GM-Tg-rg-T06421-Ab-2, GM-Tg-mg-T06421-Ab-1, GM-Tg-mg-T06421-Ab-2, GM-Tg-cynog-T06421-Ab-1, GM-Tg-cynog-T06421-Ab-2 |
| Products Name | Anti-IFNAR2 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IFNAR2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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