human, Cynomolgus/ Rhesus macaque, rat, mouse tumor necrosis factor receptor superfamily, member 6b, decoy(TNFRSF6B) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Decoy receptor 3 (Dcr3), also known as tumor necrosis factor receptor superfamily member 6B (TNFRSF6B), TR6 and M68, is a soluble protein of the tumor necrosis factor receptor superfamily which inhibits Fas ligand-induced apoptosis. This gene belongs to the tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Overexpression of this gene has been noted in various tumors e.g. gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes.


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity		SizePrice
GM-Tg-hg-SE1344-Ag-1tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-SE1344-Ab-1Anti-TNFRSF6B monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-SE1344-Ab-2Anti-TNFRSF6B monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1344-Ag-1tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1344-Ab-1Anti-TNFRSF6B monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-SE1344-Ab-2Anti-TNFRSF6B monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1344-Ag-1tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1344-Ab-1Anti-TNFRSF6B monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-SE1344-Ab-2Anti-TNFRSF6B monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1344-Ag-1tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B)Cynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1344-Ab-1Anti-TNFRSF6B monoclonal antibodyCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-SE1344-Ab-2Anti-TNFRSF6B monoclonal antibodyCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameTNFRSF6B
Full nametumor necrosis factor receptor superfamily, member 6b, decoy
Gene ID8771
Gene NameTNFRSF6B
Gene AliasDCR3, DJ583P15.1.1, M68, M68E, TR6
Protein Sub-locationSecreted Protein/Potential Cytokines

Antigen Information

Cat No.GM-Tg-hg-SE1344-Ag-1, GM-Tg-rg-SE1344-Ag-1, GM-Tg-mg-SE1344-Ag-1, GM-Tg-cynog-SE1344-Ag-1
Products Nametumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-SE1344-Ab-1, GM-Tg-hg-SE1344-Ab-2,
GM-Tg-rg-SE1344-Ab-1, GM-Tg-rg-SE1344-Ab-2,
GM-Tg-mg-SE1344-Ab-1, GM-Tg-mg-SE1344-Ab-2,
GM-Tg-cynog-SE1344-Ab-1, GM-Tg-cynog-SE1344-Ab-2
Products NameAnti-TNFRSF6B monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TNFRSF6B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.