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human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 18 binding protein(IL18BP) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to IL18BP/IL18BP products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 18 binding protein (IL18BP) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene.
The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Three transcript variants encoding the same protein have been found for this gene.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-SE1023-Ag-1 | interleukin 18 binding protein (IL18BP) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-SE1023-Ab-1 | Anti-IL18BP monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-SE1023-Ab-2 | Anti-IL18BP monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE1023-Ag-1 | interleukin 18 binding protein (IL18BP) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE1023-Ab-1 | Anti-IL18BP monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE1023-Ab-2 | Anti-IL18BP monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE1023-Ag-1 | interleukin 18 binding protein (IL18BP) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE1023-Ab-1 | Anti-IL18BP monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE1023-Ab-2 | Anti-IL18BP monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE1023-Ag-1 | interleukin 18 binding protein (IL18BP) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE1023-Ab-1 | Anti-IL18BP monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE1023-Ab-2 | Anti-IL18BP monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | IL18BP |
| Full name | interleukin 18 binding protein |
| Gene ID | 10068 |
| Gene Name | IL18BP |
| Gene Alias | IL18BPa |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
| Cat No. | GM-Tg-hg-SE1023-Ag-1, GM-Tg-rg-SE1023-Ag-1, GM-Tg-mg-SE1023-Ag-1, GM-Tg-cynog-SE1023-Ag-1 |
| Products Name | interleukin 18 binding protein (IL18BP) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse interleukin 18 binding protein (IL18BP) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-SE1023-Ab-1, GM-Tg-hg-SE1023-Ab-2, GM-Tg-rg-SE1023-Ab-1, GM-Tg-rg-SE1023-Ab-2, GM-Tg-mg-SE1023-Ab-1, GM-Tg-mg-SE1023-Ab-2, GM-Tg-cynog-SE1023-Ab-1, GM-Tg-cynog-SE1023-Ab-2 |
| Products Name | Anti-IL18BP monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL18BP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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