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human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) ligand 17(CCL17) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to CCL17/CCL17 products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) ligand 17 (CCL17) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
CCL17 is a powerful chemokine produced in the thymus and by antigen-presenting cells like dendritic cells, macrophages, and monocytes. CCL17 plays a complex role in cancer. It attracts T-regulatory cells allowing for some cancers to evade an immune response. However, in other cancers, such as melanoma, an increase in CCL17 is linked to an improved outcome. CCL17 has also been linked to allergic diseases.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-SE0742-Ag-1 | chemokine (C-C motif) ligand 17 (CCL17) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-SE0742-Ab-1 | Anti-CCL17 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-SE0742-Ab-2 | Anti-CCL17 monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0742-Ag-1 | chemokine (C-C motif) ligand 17 (CCL17) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0742-Ab-1 | Anti-CCL17 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0742-Ab-2 | Anti-CCL17 monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0742-Ag-1 | chemokine (C-C motif) ligand 17 (CCL17) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0742-Ab-1 | Anti-CCL17 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0742-Ab-2 | Anti-CCL17 monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0742-Ag-1 | chemokine (C-C motif) ligand 17 (CCL17) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0742-Ab-1 | Anti-CCL17 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0742-Ab-2 | Anti-CCL17 monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | CCL17 |
| Full name | chemokine (C-C motif) ligand 17 |
| Gene ID | 6361 |
| Gene Name | CCL17 |
| Gene Alias | A-152E5.3, ABCD-2, SCYA17, TARC |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
| Cat No. | GM-Tg-hg-SE0742-Ag-1, GM-Tg-rg-SE0742-Ag-1, GM-Tg-mg-SE0742-Ag-1, GM-Tg-cynog-SE0742-Ag-1 |
| Products Name | chemokine (C-C motif) ligand 17 (CCL17) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse chemokine (C-C motif) ligand 17 (CCL17) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-SE0742-Ab-1, GM-Tg-hg-SE0742-Ab-2, GM-Tg-rg-SE0742-Ab-1, GM-Tg-rg-SE0742-Ab-2, GM-Tg-mg-SE0742-Ab-1, GM-Tg-mg-SE0742-Ab-2, GM-Tg-cynog-SE0742-Ab-1, GM-Tg-cynog-SE0742-Ab-2 |
| Products Name | Anti-CCL17 monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL17 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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