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human, Cynomolgus/ Rhesus macaque, rat, mouse bone morphogenetic protein 8b(BMP8B) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.
Go to BMP8B/BMP8B products collection >>Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse bone morphogenetic protein 8b (BMP8B) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Bone morphogenetic protein 8B is a protein that in humans is encoded by the BMP8B gene.
The protein encoded by this gene is a member of the TGF-β superfamily. It has close sequence homology to BMP7 and BMP5 and is believed to play a role in bone and cartilage development. It has been shown to be expressed in the hippocampus of murine embryos.
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.
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| Catalog No. | Product Name | Antigen: Species Antibody: Species Reactivity | Size | Price |
| GM-Tg-hg-SE0688-Ag-1 | bone morphogenetic protein 8b (BMP8B) protein | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-SE0688-Ab-1 | Anti-BMP8B monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-hg-SE0688-Ab-2 | Anti-BMP8B monoclonal antibody | human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0688-Ag-1 | bone morphogenetic protein 8b (BMP8B) | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0688-Ab-1 | Anti-BMP8B monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-SE0688-Ab-2 | Anti-BMP8B monoclonal antibody | rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0688-Ag-1 | bone morphogenetic protein 8b (BMP8B) | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0688-Ab-1 | Anti-BMP8B monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-SE0688-Ab-2 | Anti-BMP8B monoclonal antibody | mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0688-Ag-1 | bone morphogenetic protein 8b (BMP8B) | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0688-Ab-1 | Anti-BMP8B monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-SE0688-Ab-2 | Anti-BMP8B monoclonal antibody | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
Target Information
| Target Name | BMP8B |
| Full name | bone morphogenetic protein 8b |
| Gene ID | 656 |
| Gene Name | BMP8B |
| Gene Alias | BMP8, OP2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
Antigen Information
| Cat No. | GM-Tg-hg-SE0688-Ag-1, GM-Tg-rg-SE0688-Ag-1, GM-Tg-mg-SE0688-Ag-1, GM-Tg-cynog-SE0688-Ag-1 |
| Products Name | bone morphogenetic protein 8b (BMP8B) protein |
| Species | human, Cynomolgus/ Rhesus macaque, rat, mouse |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated |
| Tag | His |
| Product Description | Recombinant human, Cynomolgus/ Rhesus macaque, rat, mouse bone morphogenetic protein 8b (BMP8B) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Antibody Information
| Catalog No. | GM-Tg-hg-SE0688-Ab-1, GM-Tg-hg-SE0688-Ab-2, GM-Tg-rg-SE0688-Ab-1, GM-Tg-rg-SE0688-Ab-2, GM-Tg-mg-SE0688-Ab-1, GM-Tg-mg-SE0688-Ab-2, GM-Tg-cynog-SE0688-Ab-1, GM-Tg-cynog-SE0688-Ab-2 |
| Products Name | Anti-BMP8B monoclonal antibody |
| Format | mab |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| Species Reactivity | Human(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m) |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-BMP8B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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