human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor receptor-like 1(FGFRL1) for cell curture,in vitro study, in vivo study,benchmark, drug discovery & MOA research and positive control for the diagnosis.


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Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor receptor-like 1 (FGFRL1) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene. The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.


Order information


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Catalog No.Product NameAntigen: Species
Antibody: Species Reactivity
SizePrice
GM-Tg-hg-MP0442-Ag-1fibroblast growth factor receptor-like 1 (FGFRL1) proteinhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-MP0442-Ab-1Anti-FGFRL1 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-hg-MP0442-Ab-2Anti-FGFRL1 monoclonal antibodyhuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-MP0442-Ag-1fibroblast growth factor receptor-like 1 (FGFRL1)rat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-MP0442-Ab-1Anti-FGFRL1 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-MP0442-Ab-2Anti-FGFRL1 monoclonal antibodyrat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-MP0442-Ag-1fibroblast growth factor receptor-like 1 (FGFRL1)mouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-MP0442-Ab-1Anti-FGFRL1 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-MP0442-Ab-2Anti-FGFRL1 monoclonal antibodymouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-MP0442-Ag-1fibroblast growth factor receptor-like 1 (FGFRL1)Cynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-MP0442-Ab-1Anti-FGFRL1 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-MP0442-Ab-2Anti-FGFRL1 monoclonal antibodyCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

Description


Target Information

Target NameFGFRL1
Full namefibroblast growth factor receptor-like 1
Gene ID53834
Gene NameFGFRL1
Gene AliasFGFR5, FHFR
Protein Sub-locationTransmembrane Protein

Antigen Information

Cat No.GM-Tg-hg-MP0442-Ag-1, GM-Tg-rg-MP0442-Ag-1, GM-Tg-mg-MP0442-Ag-1, GM-Tg-cynog-MP0442-Ag-1
Products Namefibroblast growth factor receptor-like 1 (FGFRL1) protein
Specieshuman, Cynomolgus/ Rhesus macaque, rat, mouse
IsotypesRecombinant protein
Expression platformMammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated
TagHis
Product DescriptionRecombinant human, Cynomolgus/ Rhesus macaque, rat, mouse fibroblast growth factor receptor-like 1 (FGFRL1) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research, positive control for the diagnosis.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Antibody Information

Catalog No.GM-Tg-hg-MP0442-Ab-1, GM-Tg-hg-MP0442-Ab-2,
GM-Tg-rg-MP0442-Ab-1, GM-Tg-rg-MP0442-Ab-2,
GM-Tg-mg-MP0442-Ab-1, GM-Tg-mg-MP0442-Ab-2,
GM-Tg-cynog-MP0442-Ab-1, GM-Tg-cynog-MP0442-Ab-2
Products NameAnti-FGFRL1 monoclonal antibody
Formatmab
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
Species ReactivityHuman(H), Cynomolgus/Rhesus macaque(Cyno), rat(r), mouse(m)
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FGFRL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.