Pre-made Zolimomab benchmark antibody ( Whole mAb, anti-CD5 therapeutic antibody, Anti-T3E/TCRE/IMD18/CD3epsilon Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-650

Pre-Made Zolimomab biosimilar, Whole mAb, Anti-CD5 Antibody: Anti-T3E/TCRE/IMD18/CD3epsilon therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Zolimomab aritox is a mouse monoclonal antibody which has been investigated for the treatment of systemic lupus erythematosus[1] and graft-versus-host disease,[2] but the studies failed to show positive effects of the drug.

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GMP-Bios-ab-650-1mg 1mg 3090 Inquiry Inquiry

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Description

Products Name (INN Index) Pre-Made Zolimomab biosimilar, Whole mAb, Anti-CD5 Antibody: Anti-T3E/TCRE/IMD18/CD3epsilon therapeutic antibody
INN Name Zolimomab
TargetCD5
FormatWhole mAb
Derivation
Species ReactivityHuman
CH1 IsotypeIgG2a
VD LCKappa
Highest_Clin_Trial (Jan '20)Approved
Est. StatusDiscontinued
100% SI Structure1sy6:HL
99% SI StructureNone
95-98% SI StructureNone
Year Proposed1988
Year Recommended1989
CompaniesCancer Research UK;Ortho-McNeil;XOMA
Conditions Approvedna
Conditions Activena
Conditions DiscontinuedDiabetes mellitus;Graft-versus-host disease;Renal transplant rejection;Rheumatoid arthritis
Development Techna