Pre-made Vorsetuzumab benchmark antibody ( Whole mAb ADC, anti-CD70/CD27-L therapeutic antibody, Anti-CD27L/LPFS3/CD27LG/TNFSF7/TNLG8A Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-630
Pre-Made Vorsetuzumab biosimilar, Whole mAb ADC, Anti-CD70/CD27-L Antibody: Anti-CD27L/LPFS3/CD27LG/TNFSF7/TNLG8A therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Vorsetuzumab mafodotin (SGN-75) is an antibody-drug conjugate (ADC) directed to the protein CD70 designed for the treatment of cancer. It is a humanized monoclonal antibody, vorsetuzumab, conjugated with noncleavable monomethyl auristatin F (MMAF), a cytotoxic agent.
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-ab-630-1mg | 1mg | 4635 | ||
GMP-Bios-ab-630-10mg | 10mg | Inquiry | ||
GMP-Bios-ab-630-100mg | 100mg | Inquiry | ||
GMP-Bios-ab-630-xmg | >100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Vorsetuzumab biosimilar, Whole mAb ADC, Anti-CD70/CD27-L Antibody: Anti-CD27L/LPFS3/CD27LG/TNFSF7/TNLG8A therapeutic antibody |
INN Name | Vorsetuzumab |
Target | CD27-L |
Format | Whole mAb ADC |
Derivation | Humanized |
Species Reactivity | Human |
CH1 Isotype | IgG1 |
VD LC | Kappa |
Highest_Clin_Trial (Jan '20) | Phase-II |
Est. Status | Discontinued |
100% SI Structure | None |
99% SI Structure | None |
95-98% SI Structure | None |
Year Proposed | 2012 |
Year Recommended | 2013 |
Companies | Seattle Genetics |
Conditions Approved | na |
Conditions Active | na |
Conditions Discontinued | Autoimmune disorders;Cancer;Inflammation;Plaque psoriasis |
Development Tech | na |
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