Pre-made Timolumab benchmark antibody ( Whole mAb, anti-AOC3 therapeutic antibody, Anti-HPAO/SSAO/VAP-1/VAP1 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-577

Pre-Made Timolumab biosimilar, Whole mAb, Anti-AOC3 Antibody: Anti-HPAO/SSAO/VAP-1/VAP1 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

TECHNOLOGY. DESCRIPTION. Timolumab (BTT-1023; SI-3106; SI-636) is a fully human, monoclonal, anti-vascular adhesion protein- 1 (VAP-1) antibody which works by blocking the adhesion function of VAP-1 which diminishes. leucocyte entry to sites of inflammation.

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GMP-Bios-ab-577-1mg 1mg 3090 Inquiry Inquiry

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Timolumab biosimilar, Whole mAb, Anti-AOC3 Antibody: Anti-HPAO/SSAO/VAP-1/VAP1 therapeutic antibody
INN Name Timolumab
TargetAOC3
FormatWhole mAb
DerivationHuman
Species ReactivityHuman
CH1 IsotypeIgG4
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-II
Est. StatusDiscontinued
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2015
Year Recommended2016
CompaniesAcorda Therapeutics;Biotie Therapies Corp.;Seikagaku Corporation
Conditions Approvedna
Conditions Activena
Conditions DiscontinuedInflammation;Plaque psoriasis;Rheumatoid arthritis;Primary sclerosing cholangitis
Development Techna