Pre-made Telazorlimab benchmark antibody ( Whole mAb, anti-TNFRSF4/CD134 therapeutic antibody, Anti-ACT35/IMD16/OX40/TXGP1L Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-558

Pre-Made Telazorlimab biosimilar, Whole mAb, Anti-TNFRSF4/CD134 Antibody: Anti-ACT35/IMD16/OX40/TXGP1L therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Telazorlimab (previously ISB 830 or GBR 830) is an OX40 antagonist monoclonal antibody, being developed by Ichnos Sciences (a spin-off of Glenmark.

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GMP-Bios-ab-558-1mg 1mg 3090 Inquiry Inquiry

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Description

Products Name (INN Index) Pre-Made Telazorlimab biosimilar, Whole mAb, Anti-TNFRSF4/CD134 Antibody: Anti-ACT35/IMD16/OX40/TXGP1L therapeutic antibody
INN Name Telazorlimab
TargetCD134
FormatWhole mAb
Derivation
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-II
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2019
Year Recommended2020
CompaniesGlenmark Pharmaceuticals
Conditions Approvedna
Conditions ActiveAtopic dermatitis;Systemic lupus erythematosus;Ulcerative colitis;Rheumatoid arthritis
Conditions Discontinuedna
Development Techna