Pre-made Tarlatamab benchmark antibody ( Bispecific scFv, anti-DLL3;CD3E therapeutic antibody, Anti-SCDO1;T3E/TCRE/IMD18 Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-552
Pre-Made Tarlatamab biosimilar, Bispecific scFv, Anti-DLL3;CD3E Antibody: Anti-SCDO1;T3E/TCRE/IMD18 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Tarlatamab is a half-life extended delta-like protein 3 (DLL3)/anti-CD3 bispecific T-cell engager (HLE BiTE) antibody construct, being developed by Amgen for the treatment of small cell lung cancer, neuroendocrine prostate cancer and metastatic melanoma.
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-ab-552-1mg | 1mg | Inquiry | ||
GMP-Bios-ab-552-10mg | 10mg | Inquiry | ||
GMP-Bios-ab-552-100mg | 100mg | Inquiry | ||
GMP-Bios-ab-552-xmg | >100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Tarlatamab biosimilar, Bispecific scFv, Anti-DLL3;CD3E Antibody: Anti-SCDO1;T3E/TCRE/IMD18 therapeutic antibody |
INN Name | Tarlatamab |
Target | DLL3;CD3E |
Format | Bispecific scFv |
Derivation | Bispecific antibody |
Species Reactivity | Human |
CH1 Isotype | na;na |
VD LC | Kappa;Lambda |
Highest_Clin_Trial (Jan '20) | Phase-I |
Est. Status | Active |
100% SI Structure | None;None |
99% SI Structure | None;None |
95-98% SI Structure | None;None |
Year Proposed | 2020 |
Year Recommended | 2021 |
Companies | Amgen |
Conditions Approved | na |
Conditions Active | Small cell lung cancer |
Conditions Discontinued | na |
Development Tech | BiTE Technology |
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