Pre-made Sabatolimab benchmark antibody ( Whole mAb, anti-HAVCR2/TIM3 therapeutic antibody, Anti-CD366/KIM-3/SPTCL/TIMD3/Tim-3/TIMD-3/HAVcr-2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-502

Pre-Made Sabatolimab biosimilar, Whole mAb, Anti-HAVCR2/TIM3 Antibody: Anti-CD366/KIM-3/SPTCL/TIMD3/Tim-3/TIMD-3/HAVcr-2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Sabatolimab (MBG 453) is a anti T-cell immunoglobulin and mucin domain 3 ( anti-TIM3) monoclonal antibody that is being developed by Novartis Oncology.

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GMP-Bios-ab-502-1mg 1mg 3090 Inquiry Inquiry

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Description

Products Name (INN Index) Pre-Made Sabatolimab biosimilar, Whole mAb, Anti-HAVCR2/TIM3 Antibody: Anti-CD366/KIM-3/SPTCL/TIMD3/Tim-3/TIMD-3/HAVcr-2 therapeutic antibody
INN Name Sabatolimab
TargetHAVCR2
FormatWhole mAb
Derivation
Species ReactivityHuman
CH1 IsotypeIgG4
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-III
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2019
Year Recommendedna
CompaniesNovartis
Conditions Approvedna
Conditions ActiveChronic myelomonocytic leukaemia;Myelodysplastic syndromes;Acute myeloid leukaemia;Myelofibrosis;Solid tumours;Glioblastoma
Conditions Discontinuedna
Development Techna