Pre-made Pacanalotamab benchmark antibody ( Bispecific scFv, anti-TNFRSF17;CD3E therapeutic antibody, Anti-BCM/BCMA/CD269/TNFRSF13A;T3E/TCRE/IMD18 Antibody) for drug discovery and mechanism of action (MOA) research

Pre-Made Pacanalotamab biosimilar, Bispecific scFv, Anti-TNFRSF17;CD3E Antibody: Anti-BCM/BCMA/CD269/TNFRSF13A;T3E/TCRE/IMD18 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Pacanalotamab is an anti-BCMA-anti-CD3-bispecific-antibody, where the bispecific T-cell engager (BiTE) binds to the CD3 epsilon subunit of the T cell receptor complex on T-cells and to B-cell maturation antigen (BCMA), a membrane-bound receptor on plasma cells, resulting in activation of T cells against BCMA.

Order information

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Catalog No.	Package	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-Bios-ab-421-1mg	1mg	Inquiry
GMP-Bios-ab-421-10mg	10mg	Inquiry
GMP-Bios-ab-421-100mg	100mg	Inquiry
GMP-Bios-ab-421-xmg	＞100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Products Name (INN Index)	Pre-Made Pacanalotamab biosimilar, Bispecific scFv, Anti-TNFRSF17;CD3E Antibody: Anti-BCM/BCMA/CD269/TNFRSF13A;T3E/TCRE/IMD18 therapeutic antibody
INN Name	Pacanalotamab
Target	TNFRSF17;CD3E
Format	Bispecific scFv
Derivation	Bispecific antibody
Species Reactivity	Human
CH1 Isotype	na;na
VD LC	Kappa;Lambda
Highest_Clin_Trial (Jan '20)	Phase-I
Est. Status	Active
100% SI Structure	None;None
99% SI Structure	None;None
95-98% SI Structure	None;None
Year Proposed	2020
Year Recommended	2021
Companies	Amgen
Conditions Approved	na
Conditions Active	Multiple myeloma
Conditions Discontinued	na
Development Tech	BiTE Technology