Pre-made Oportuzumab benchmark antibody ( scFv, anti-EPCAM therapeutic antibody, Anti-Ber-Ep4/BerEp4/DIAR5/EGP-2/EGP314/EGP40/ESA/HNPCC8/KS1/4/KSA/M4S1/MIC18/MK-1/MOC-31/TACSTD1/TROP1 Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-408
Pre-Made Oportuzumab biosimilar, scFv, Anti-EPCAM Antibody: Anti-Ber-Ep4/BerEp4/DIAR5/EGP-2/EGP314/EGP40/ESA/HNPCC8/KS1/4/KSA/M4S1/MIC18/MK-1/MOC-31/TACSTD1/TROP1 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
A fusion protein immunotoxin consisting of a humanized, single-chain monoclonal antibody fragment specific for the epithelial cell adhesion molecule (EpCAM) conjugated with a truncated form of Pseudomonas exotoxin A with potential antineoplastic activity.
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-ab-408-1mg | 1mg | 3090 | ||
GMP-Bios-ab-408-10mg | 10mg | Inquiry | ||
GMP-Bios-ab-408-100mg | 100mg | Inquiry | ||
GMP-Bios-ab-408-xmg | >100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Oportuzumab biosimilar, scFv, Anti-EPCAM Antibody: Anti-Ber-Ep4/BerEp4/DIAR5/EGP-2/EGP314/EGP40/ESA/HNPCC8/KS1/4/KSA/M4S1/MIC18/MK-1/MOC-31/TACSTD1/TROP1 therapeutic antibody |
INN Name | Oportuzumab |
Target | EPCAM |
Format | scFv |
Derivation | |
Species Reactivity | Human |
CH1 Isotype | na |
VD LC | Kappa |
Highest_Clin_Trial (Jan '20) | Preregistration |
Est. Status | Active |
100% SI Structure | None |
99% SI Structure | None |
95-98% SI Structure | None |
Year Proposed | 2008 |
Year Recommended | 2009 |
Companies | University of Zurich;National Cancer Institute (USA);Sesen Bio;Viventia Biotechnologies |
Conditions Approved | na |
Conditions Active | Bladder cancer;Head and neck cancer |
Conditions Discontinued | Liver cancer;Ovarian cancer |
Development Tech | na |
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