Pre-made Opicinumab benchmark antibody ( Whole mAb, anti-LINGO1 therapeutic antibody, Anti-LERN1/LRRN6A/MRT64/UNQ201 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-407

Pre-Made Opicinumab biosimilar, Whole mAb, Anti-LINGO1 Antibody: Anti-LERN1/LRRN6A/MRT64/UNQ201 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Opicinumab (BIIB033) is a fully human monoclonal antibody designed for the treatment of multiple sclerosis, acute optic neuritis (AON), and other associated demyelinating diseases. A biologic drug, it is designed to function as a LINGO-1 protein antagonist, known as “Anti-Lingo-1”.

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GMP-Bios-ab-407-1mg 1mg 3090 Inquiry Inquiry

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Opicinumab biosimilar, Whole mAb, Anti-LINGO1 Antibody: Anti-LERN1/LRRN6A/MRT64/UNQ201 therapeutic antibody
INN Name Opicinumab
TargetLINGO1
FormatWhole mAb
DerivationHuman
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-II
Est. StatusDiscontinued
100% SI Structure4oqt:HL
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2015
Year Recommended2016
CompaniesBiogen Idec;Dyax;Biogen
Conditions Approvedna
Conditions Activena
Conditions DiscontinuedMultiple sclerosis;Optic neuritis
Development TechDyax Human Phage Display