Pre-made Ontamalimab benchmark antibody ( Whole mAb, anti-MADCAM1 therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-404

Pre-Made Ontamalimab biosimilar, Whole Mab: Anti-MADCAM1 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Ontamalimab is a fully human immunoglobulin G2 monoclonal antibody against mucosal addressin cell adhesion molecule-1 in development for the induction and maintenance of clinical remission in patients with ulcerative colitis (UC).

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GMP-Bios-ab-404-1mg 1mg 3090 Inquiry Inquiry

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Ontamalimab biosimilar, Whole Mab: Anti-MADCAM1 therapeutic antibody
INN Name Ontamalimab
TargetMADCAM1
FormatWhole mAb
DerivationHuman
Species ReactivityHuman
CH1 IsotypeIgG2
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-III
Est. StatusDiscontinued
100% SI Structure4hcr:MN:HL
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2018
Year Recommended2019
CompaniesPfizer;Takeda
Conditions Approvedna
Conditions Activena
Conditions DiscontinuedCrohn's disease;Ulcerative colitis
Development Techna