Pre-made Omburtamab benchmark antibody ( Whole mAb Radiolabelled, anti-CD276 therapeutic antibody, Anti-4Ig-B7-H3/B7-H3/B7H3/B7RP-2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-399

Pre-Made Omburtamab biosimilar, Whole mAb Radiolabelled, Anti-CD276 Antibody: Anti-4Ig-B7-H3/B7-H3/B7H3/B7RP-2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Omburtamab (formerly burtomab) is a theranostic monoclonal antibody 8H9, conjugated to to 131 iodine, being developed by Y-mAbs Therapeutics, under a license from Memorial Sloan-Kettering Cancer Center, for the diagnosis and treatment of cancer.

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* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry

Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-Bios-ab-399-1mg 1mg Inquiry
GMP-Bios-ab-399-10mg 10mg Inquiry
GMP-Bios-ab-399-100mg 100mg Inquiry
GMP-Bios-ab-399-xmg >100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Products Name (INN Index) Pre-Made Omburtamab biosimilar, Whole mAb Radiolabelled, Anti-CD276 Antibody: Anti-4Ig-B7-H3/B7-H3/B7H3/B7RP-2 therapeutic antibody
INN Name Omburtamab
TargetCD276
FormatWhole mAb Radiolabelled
DerivationMouse
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-II/III
Est. StatusActive
100% SI Structure5cma:BA
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2018
Year Recommended2019
CompaniesMemorial Sloan-Kettering Cancer Center;Y-mAbs Therapeutics
Conditions Approvedna
Conditions ActiveNeuroblastoma;Meningeal carcinomatosis;Soft tissue sarcoma;Peritoneal cancer
Conditions DiscontinuedSolid tumours
Development Techna