Pre-made Nivatrotamab benchmark antibody ( Bispecific Mixed mAb and scFv, anti-GD2;CD3E therapeutic antibody, Anti-T3E/TCRE/IMD18/CD3epsilon Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-380
Pre-Made Nivatrotamab biosimilar, Bispecific Mixed mAb and scFv, Anti-GD2;CD3E Antibody: Anti-T3E/TCRE/IMD18/CD3epsilon therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Nivatrotamab, a humanized bispecific anti-GD2 antibody, is currently in Phase 1 clinical development in collaboration with Memorial Sloan Kettering Cancer Center (“MSK”) in patients with relapsed/refractory neuroblastoma, as well as high grade osteosarcoma and other GD2(+) solid tumors, where patients have relapsed or refractory disease that is resistant to standard therapy.
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-ab-380-1mg | 1mg | Inquiry | ||
GMP-Bios-ab-380-10mg | 10mg | Inquiry | ||
GMP-Bios-ab-380-100mg | 100mg | Inquiry | ||
GMP-Bios-ab-380-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Nivatrotamab biosimilar, Bispecific Mixed mAb and scFv, Anti-GD2;CD3E Antibody: Anti-T3E/TCRE/IMD18/CD3epsilon therapeutic antibody |
INN Name | Nivatrotamab |
Target | GD2;CD3E |
Format | Bispecific Mixed mAb and scFv |
Derivation | Bispecific antibody |
Species Reactivity | Human |
CH1 Isotype | IgG1;na |
VD LC | Kappa;Kappa |
Highest_Clin_Trial (Jan '20) | Phase-I/II |
Est. Status | Active |
100% SI Structure | None;None |
99% SI Structure | None;None |
95-98% SI Structure | None;None |
Year Proposed | 2020 |
Year Recommended | na |
Companies | Memorial Sloan-Kettering Cancer Center |
Conditions Approved | na |
Conditions Active | Neuroblastoma |
Conditions Discontinued | na |
Development Tech | na |
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