Pre-made Magrolimab benchmark antibody ( Whole mAb, anti-CD47 therapeutic antibody, Anti-IAP/OA3/MER6 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-333

Pre-Made Magrolimab biosimilar, Whole mAb, Anti-CD47 Antibody: Anti-IAP/OA3/MER6 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.



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GMP-Bios-ab-333-1mg 1mg 3090 Inquiry Inquiry

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Description

Products Name (INN Index) Pre-Made Magrolimab biosimilar, Whole mAb, Anti-CD47 Antibody: Anti-IAP/OA3/MER6 therapeutic antibody
INN Name Magrolimab
TargetCD47
FormatWhole mAb
Derivation
Species ReactivityHuman
CH1 IsotypeIgG4
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-III
Est. StatusActive
100% SI StructureNone
99% SI Structure5iwl:AA:BB
95-98% SI StructureNone
Year Proposed2018
Year Recommended2019
CompaniesForty Seven;Merck KGaA;Stanford University
Conditions Approvedna
Conditions ActiveDiffuse large B cell lymphoma;Follicular lymphoma;Non-Hodgkin's lymphoma;Colorectal cancer;Solid tumours;Acute myeloid leukaemia;Myelodysplastic syndromes;Ovarian cancer
Conditions DiscontinuedLymphoma
Development Techna