Pre-made Intetumumab benchmark antibody ( Whole mAb, anti-ITGAV_ITGB3 therapeutic antibody, Anti-CD51/MSK8/VNRA/VTNR;BDPLT16/BDPLT2/BDPLT24/CD61/GP3A/GPIIIa/GT/GT2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-276

Pre-made Intetumumab benchmark antibody (Whole mAb, anti-ITGAV_ITGB3 therapeutic antibody, Anti-CD51/MSK8/VNRA/VTNR;BDPLT16/BDPLT2/BDPLT24/CD61/GP3A/GPIIIa/GT/GT2 Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Intetumumab is a human monoclonal antibody targeting integrins that was being studied for the treatment of solid tumors.

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GMP-Bios-ab-276-1mg 1mg 3090 Inquiry Inquiry

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Intetumumab biosimilar, Whole mAb, Anti-ITGAV;ITGB3 Antibody: Anti-CD51/MSK8/VNRA/VTNR;BDPLT16/BDPLT2/BDPLT24/CD61/GP3A/GPIIIa/GT/GT2 therapeutic antibody
INN Name Intetumumab
TargetITGAV_ITGB3
FormatWhole mAb
DerivationHuman
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-II
Est. StatusDiscontinued
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2009
Year Recommended2010
CompaniesCentocor Inc;Janssen Biotech;Janssen-Cilag
Conditions Approvedna
Conditions Activena
Conditions DiscontinuedMalignant melanoma;Prostate cancer
Development TechVelocImmune Mouse