Pre-made Imsidolimab benchmark antibody ( Whole mAb, anti-IL36R/IL1RL2 therapeutic antibody, Anti-IL1RRP2/IL-1Rrp2/IL1R-rp2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-269

Pre-Made Imsidolimab biosimilar, Whole mAb, Anti-IL36R/IL1RL2 Antibody: Anti-IL1RRP2/IL-1Rrp2/IL1R-rp2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Imsidolimab, previously known as ANB019, is an antibody that inhibits the function of the interleukin-36-receptor, or IL-36R, which we are initially developing as a potential first-in-class therapy for patients suffering from generalized pustular psoriasis (GPP), EGFRi-mediated skin toxicity, ichthyosis, hidradenitis suppurativa and acne.

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* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry

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GMP-Bios-ab-269-1mg 1mg 3090 Inquiry Inquiry

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Imsidolimab biosimilar, Whole mAb, Anti-IL36R/IL1RL2 Antibody: Anti-IL1RRP2/IL-1Rrp2/IL1R-rp2 therapeutic antibody
INN Name Imsidolimab
TargetIL1RL2
FormatWhole mAb
Derivation
Species ReactivityHuman
CH1 IsotypeIgG4
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-II
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2020
Year Recommendedna
CompaniesAnaptysBio
Conditions Approvedna
Conditions ActiveGeneralised pustular psoriasis;Localised pustular psoriasis
Conditions Discontinuedna
Development Techna