Pre-made Faricimab benchmark antibody ( Bispecific mAb, anti-VEGFA;ANGPT2 therapeutic antibody, Anti-VPF/VEGF/MVCD1;AGPT2/ANG2/LMPHM10 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-204

Pre-Made Faricimab biosimilar, Bispecific mAb, Anti-VEGFA;ANGPT2 Antibody: Anti-VPF/VEGF/MVCD1;AGPT2/ANG2/LMPHM10 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Faricimab (INN) is a bispecific monoclonal antibody that is being investigated for diabetic macular edema.

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Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-Bios-ab-204-1mg 1mg Inquiry
GMP-Bios-ab-204-10mg 10mg Inquiry
GMP-Bios-ab-204-100mg 100mg Inquiry
GMP-Bios-ab-204-xmg ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Products Name (INN Index) Pre-Made Faricimab biosimilar, Bispecific mAb, Anti-VEGFA;ANGPT2 Antibody: Anti-VPF/VEGF/MVCD1;AGPT2/ANG2/LMPHM10 therapeutic antibody
INN Name Faricimab
TargetVEGFA;ANGPT2
FormatBispecific mAb
DerivationBispecific antibody
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa;Lambda
Highest_Clin_Trial (Jan '20)Preregistration
Est. StatusActive
100% SI Structure1cz8:HL:YX;None
99% SI StructureNone;None
95-98% SI Structure1bj1:HL:KJ/6bft:AB:HL;4iml:AB:HL/4imk:AD:BC
Year Proposed2017
Year Recommended2018
CompaniesChugai Pharmaceutical;Roche
Conditions Approvedna
Conditions ActiveDiabetic macular oedema;Wet age-related macular degeneration;Retinal oedema
Conditions Discontinuedna
Development TechDual-Affinity Re-Targeting Technology