Pre-made Evinacumab benchmark antibody ( Whole mAb, anti-ANGPTL3 therapeutic antibody, Anti-ANG-5/ANGPT5/ANL3/FHBL2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-201

Pre-Made Evinacumab biosimilar, Whole mAb, Anti-ANGPTL3 Antibody: Anti-ANG-5/ANGPT5/ANL3/FHBL2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Evinacumab, sold under the brand name Evkeeza, is a monoclonal antibody medication for the treatment of homozygous familial hypercholesterolemia (HoFH).

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GMP-Bios-ab-201-1mg 1mg 3090 Inquiry Inquiry

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Description

Products Name (INN Index) Pre-Made Evinacumab biosimilar, Whole mAb, Anti-ANGPTL3 Antibody: Anti-ANG-5/ANGPT5/ANL3/FHBL2 therapeutic antibody
INN Name Evinacumab
TargetANGPTL3
FormatWhole mAb
DerivationHuman
Species ReactivityHuman
CH1 IsotypeIgG4
VD LCKappa
Highest_Clin_Trial (Jan '20)Approved
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2014
Year Recommended2015
CompaniesRegeneron Pharmaceuticals;Sanofi
Conditions ApprovedHyperlipoproteinaemia type II
Conditions ActiveHypertriglyceridaemia
Conditions Discontinuedna
Development Techna