Pre-made Etaracizumab benchmark antibody ( Whole mAb, anti-ITGAV_ITGB3 therapeutic antibody, Anti-CD51/MSK8/VNRA/VTNR;BDPLT16/BDPLT2/BDPLT24/CD61/GP3A/GPIIIa/GT/GT2 Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-195
Pre-made Etaracizumab benchmark antibody (Whole mAb, anti-ITGAV_ITGB3 therapeutic antibody, Anti-CD51/MSK8/VNRA/VTNR;BDPLT16/BDPLT2/BDPLT24/CD61/GP3A/GPIIIa/GT/GT2 Antibody) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Etaracizumab, also known as etaratuzumab,[citation needed] MEDI-522, trade name Abegrin, is a humanized monoclonal antibody which is being investigated for the treatment of metastatic melanoma, prostate cancer, ovarian cancer and various other types of cancer. It is manufactured by MedImmune.
Order information
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| Catalog No. | Package | List Price(In USD) | Discount off | Discount Price |
|---|---|---|---|---|
| GMP-Bios-ab-195-1mg | 1mg | 3090 | Inquiry | Inquiry |
Size: 1mg | 10mg | 100mg
Description
| Products Name (INN Index) | Pre-Made Etaracizumab biosimilar, Whole mAb, Anti-ITGAV;ITGB3 Antibody: Anti-CD51/MSK8/VNRA/VTNR;BDPLT16/BDPLT2/BDPLT24/CD61/GP3A/GPIIIa/GT/GT2 therapeutic antibody |
| INN Name | Etaracizumab |
| Target | ITGAV_ITGB3 |
| Format | Whole mAb |
| Derivation | Humanized |
| Species Reactivity | Human |
| CH1 Isotype | IgG1 |
| VD LC | Kappa |
| Highest_Clin_Trial (Jan '20) | Phase-II |
| Est. Status | Discontinued |
| 100% SI Structure | None |
| 99% SI Structure | None |
| 95-98% SI Structure | None |
| Year Proposed | 2008 |
| Year Recommended | 2009 |
| Companies | Applied Molecular Evolution;MedImmune |
| Conditions Approved | na |
| Conditions Active | na |
| Conditions Discontinued | Colorectal cancer;Malignant melanoma;Prostate cancer;Psoriasis;Rheumatoid arthritis |
| Development Tech | na |

