Pre-made Cevostamab benchmark antibody ( Bispecific mAb, anti-FCRL5;CD3 therapeutic antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-103
Pre-Made Cevostamab biosimilar, Bispecific mAb: Anti-FCRL5;CD3 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
A proprietary recombinant bispecific T-cell engager (BiTE) antibody composed of two single-chain variable fragments (scFv), one directed against the tumor-associated antigen (TAA) Fc receptor-like protein 5 (FCRH5; CD307; FCRL5; IRTA2; BXMAS1) and one that is directed against the CD3 antigen found on T lymphocytes, with potential immunostimulating and antineoplastic activities.
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-ab-103-1mg | 1mg | Inquiry | ||
GMP-Bios-ab-103-10mg | 10mg | Inquiry | ||
GMP-Bios-ab-103-100mg | 100mg | Inquiry | ||
GMP-Bios-ab-103-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Cevostamab biosimilar, Bispecific mAb: Anti-FCRL5;CD3 therapeutic antibody |
INN Name | Cevostamab |
Target | FCRL5;CD3 |
Format | Bispecific mAb |
Derivation | Bispecific antibody |
Species Reactivity | Human |
CH1 Isotype | IgG1 |
VD LC | Kappa;Kappa |
Highest_Clin_Trial (Jan '20) | Phase-I |
Est. Status | Active |
100% SI Structure | None;None |
99% SI Structure | None;None |
95-98% SI Structure | None;None |
Year Proposed | 2019 |
Year Recommended | 2020 |
Companies | Genentech |
Conditions Approved | na |
Conditions Active | Multiple myeloma |
Conditions Discontinued | na |
Development Tech | na |
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