Pre-made Certolizumab benchmark antibody ( Fab, anti-TNFA/TNF therapeutic antibody, Anti-DIF/TNFSF2/TNLG1F Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-100
Pre-Made Certolizumab biosimilar, Fab, Anti-TNFA/TNF Antibody: Anti-DIF/TNFSF2/TNLG1F therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Certolizumab pegol, sold under the brand name Cimzia, is a biologic medication for the treatment of Crohn's disease, rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. It is a fragment of a monoclonal antibody specific to tumor necrosis factor alpha (TNF-α) and is manufactured by UCB.
Order information
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Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-ab-100-1mg | 1mg | 3090 | ||
GMP-Bios-ab-100-10mg | 10mg | Inquiry | ||
GMP-Bios-ab-100-100mg | 100mg | Inquiry | ||
GMP-Bios-ab-100-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Certolizumab biosimilar, Fab, Anti-TNFA/TNF Antibody: Anti-DIF/TNFSF2/TNLG1F therapeutic antibody |
INN Name | Certolizumab |
Target | TNF |
Format | Fab |
Derivation | |
Species Reactivity | Human |
CH1 Isotype | IgG1 |
VD LC | Kappa |
Highest_Clin_Trial (Jan '20) | Approved |
Est. Status | Active |
100% SI Structure | 5wuv:HL/5wux:HL:AB:CD |
99% SI Structure | None |
95-98% SI Structure | None |
Year Proposed | 2004 |
Year Recommended | 2004 |
Companies | UCB |
Conditions Approved | Ankylosing spondylitis;Crohn's disease;Plaque psoriasis;Psoriatic arthritis;Rheumatoid arthritis;Spondylitis;Non-radiographic axial spondyloarthritis |
Conditions Active | Interstitial cystitis;Juvenile rheumatoid arthritis |
Conditions Discontinued | Cognition disorders |
Development Tech | na |
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