Pre-made Bezlotoxumab benchmark antibody ( Whole mAb, anti-Toxin A therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-067

Pre-Made Bezlotoxumab biosimilar, Whole Mab: Anti-Toxin A therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Bezlotoxumab, sold under the brand name Zinplava, is a human monoclonal antibody designed for the prevention of recurrence of Clostridium difficile infections.

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GMP-Bios-ab-067-1mg 1mg 3090 Inquiry Inquiry

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Bezlotoxumab biosimilar, Whole Mab: Anti-Toxin A therapeutic antibody
INN Name Bezlotoxumab
TargetToxin A
FormatWhole mAb
DerivationHuman
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa
Highest_Clin_Trial (Jan '20)Approved
Est. StatusNFD
100% SI Structure4np4:HL:IM
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2012
Year Recommended2013
CompaniesMedarex;University of Massachusetts Medical School;Merck & Co;Merck Sharp & Dohme
Conditions ApprovedClostridium difficile
Conditions Activena
Conditions Discontinuedna
Development TechMedarex HuMAb Mouse