Pre-made Begelomab benchmark antibody ( Whole mAb, anti-DPP4/DPP-4 therapeutic antibody, Anti-ADABP/ADCP2/CD26/DPPIV/TP103 Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-054
Pre-Made Begelomab biosimilar, Whole mAb, Anti-DPP4/DPP-4 Antibody: Anti-ADABP/ADCP2/CD26/DPPIV/TP103 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
A monoclonal antibody against the human dipeptidyl peptidase 4 (dipeptidylpeptidase IV, DPPIV, DPP4; CD26), with potential activity against graft-versus-host disease (GvHD). Upon administration, begelomab binds to CD26 expressed on T-cells. This inhibits the stimulation of T-cells and may prevent GvHD.
Order information
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Catalog No. | Package | List Price(In USD) | Discount off | Discount Price |
---|---|---|---|---|
GMP-Bios-ab-054-1mg | 1mg | 3090 | Inquiry | Inquiry |
Size: 1mg | 10mg | 100mg
Description
Products Name (INN Index) | Pre-Made Begelomab biosimilar, Whole mAb, Anti-DPP4/DPP-4 Antibody: Anti-ADABP/ADCP2/CD26/DPPIV/TP103 therapeutic antibody |
INN Name | Begelomab |
Target | DPP-4 |
Format | Whole mAb |
Derivation | Mouse |
Species Reactivity | Human |
CH1 Isotype | IgG2b |
VD LC | Kappa |
Highest_Clin_Trial (Jan '20) | Phase-II/III |
Est. Status | Active |
100% SI Structure | None |
99% SI Structure | None |
95-98% SI Structure | None |
Year Proposed | 2014 |
Year Recommended | 2015 |
Companies | ADIENNE |
Conditions Approved | na |
Conditions Active | Graft-versus-host disease |
Conditions Discontinued | na |
Development Tech | na |
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