Pre-made Bedinvetmab benchmark antibody ( Canine Whole mAb, anti-Canine NGFB therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-052

Pre-Made Bedinvetmab biosimilar, Canine Whole Mab: Anti-Canine NGFB therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Bedinvetmab is a canine monoclonal antibody (mAb) targeting Nerve Growth Factor (NGF). The inhibition of NGF mediated cell signalling has demonstrated to provide relief from pain associated with osteoarthritis. ... The presence of binding antibodies to bedinvetmab in dogs was assessed using a multitier approach.

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Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-Bios-ab-052-1mg 1mg 3090
GMP-Bios-ab-052-10mg 10mg Inquiry
GMP-Bios-ab-052-100mg 100mg Inquiry
GMP-Bios-ab-052-xmg ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Products Name (INN Index) Pre-Made Bedinvetmab biosimilar, Canine Whole Mab: Anti-Canine NGFB therapeutic antibody
INN Name Bedinvetmab
TargetCanine NGFB
FormatCanine Whole mAb
DerivationCaninized
Species ReactivityCanine
CH1 IsotypeIgG2
VD LCLambda
Highest_Clin_Trial (Jan '20)Approved
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2018
Year Recommended2019
Companiesna
Conditions Approvedna
Conditions ActiveCanine lupus familiaris
Conditions Discontinuedna
Development Techna