Pre-made Apitegromab benchmark antibody ( Whole mAb, anti-pro-GDF-8 therapeutic antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-030
Pre-Made Apitegromab biosimilar, Whole Mab: Anti-pro-GDF-8 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Apitegromab (SRK 015) is an anti-promyostatin monoclonal antibody that is being developed by Scholar Rock, for the treatment of spinal muscular atrophy (SMA), muscle-wasting disorders and spinal cord injuries.
Order information
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Catalog No. | Package | List Price(In USD) | Discount off | Discount Price |
---|---|---|---|---|
GMP-Bios-ab-030-1mg | 1mg | 3090 | Inquiry | Inquiry |
Size: 1mg | 10mg | 100mg
Description
Products Name (INN Index) | Pre-Made Apitegromab biosimilar, Whole Mab: Anti-pro-GDF-8 therapeutic antibody |
INN Name | Apitegromab |
Target | pro-GDF-8 |
Format | Whole mAb |
Derivation | |
Species Reactivity | Human |
CH1 Isotype | IgG4 |
VD LC | Lambda |
Highest_Clin_Trial (Jan '20) | Phase-II |
Est. Status | Active |
100% SI Structure | None |
99% SI Structure | None |
95-98% SI Structure | 6umx:HL:hl |
Year Proposed | 2020 |
Year Recommended | 2021 |
Companies | Scholar Rock |
Conditions Approved | na |
Conditions Active | Spinal muscular atrophy;Muscular atrophy;Spinal cord injuries |
Conditions Discontinued | na |
Development Tech | na |
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