Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi (Biotinylated) for antibody Fc&Fc
Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay)  

Cat No.: GMP-BioFcR-ag-031

Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi (Biotinylated) is used to measure the affinity of antibodies for it.

The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of
therapeutic antibodies.

GeneMedi provides Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi (Biotinylated)
The receptor has been classified based on its affinity for IgG1, IgG3, IgG4. The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.


Order information



GeneMedi provides two kinds of Human Neonatal Fc receptor (FcRn) Heterodimer (GMP-BioFcR-ag-031), GMP-BioFcR-ag-031-1 is with the tag His and Avi, GMP-BioFcR-ag-031-2 is Biotinylated and also with the tag His and Avi.

Catalog No. Description Price
(In USD)		 Qty (Quantity) Sum(In USD)
GMP-BioFcR-ag-031-1 Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi    Size:1mg 5990
GMP-BioFcR-ag-031-1 Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi    Size:10mg 38790
GMP-BioFcR-ag-031-1 Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi     Size:100mg 258000
GMP-BioFcR-ag-031-2 Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi, Biotinylated    Size:1mg 6990
GMP-BioFcR-ag-031-2 Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi, Biotinylated    Size:10mg 43790
GMP-BioFcR-ag-031-2 Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi, Biotinylated    Size:100mg 293000
GMP-BioFcR-ag-031 Size≥100mg Inquiry
Shipping Cost: 760.00
Total:

For more than 100mg, click here for inquiry. >>


Description

Products Name GMP-BioFcR-ag-031-1: Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi
GMP-BioFcR-ag-031-2: Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi, Biotinylated
Products Description Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi (Biotinylated) is used to measure the affinity of antibodies for it. The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of therapeutic antibodies. GeneMedi provides Human Neonatal Fc receptor (FcRn) Heterodimer  His+Avi (Biotinylated). The receptor has been classified based on its affinity for IgG1, IgG2, IgG3, IgG4 . The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.
Isotype Neonatal Fc receptor (FcRn)
Receptor name Neonatal Fc receptor (FcRn) Heterodimer 
Species Human
Principal antibody ligand IgG1, IgG2, IgG3, IgG4
Major role Transport/ recycling
Effect following binding to antibody Transfers IgG from a mother to fetus through the placenta, Transfers IgG from a mother to infant in milk, Protects IgG from degradation
WT/Mutation WT
Mutant variants functions vs WT N/A
Fc Modifications or Mutations 
(Reduced effector function)
Fc Modifications or Mutations 
(Enhanced effector function) 		IgG1/IgA2 (ADCC)
Application Antibody Fc&Fc Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay)  
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.