Products
Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi (Biotinylated) for antibody Fc&Fc
Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay)
Cat No.: GMP-BioFcR-ag-031
Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi (Biotinylated) is used to measure the affinity of antibodies for it.
The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of
therapeutic antibodies.
GeneMedi provides Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi (Biotinylated)
The receptor has been classified based on its affinity for IgG1, IgG3, IgG4. The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.
Order information
GeneMedi provides two kinds of Human Neonatal Fc receptor (FcRn) Heterodimer (GMP-BioFcR-ag-031), GMP-BioFcR-ag-031-1 is with the tag His and Avi, GMP-BioFcR-ag-031-2 is Biotinylated and also with the tag His and Avi.
| Catalog No. | Description | Price (In USD) |
Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| GMP-BioFcR-ag-031-1 | Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi Size:1mg | 5990 | ||
| GMP-BioFcR-ag-031-1 | Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi Size:10mg | 38790 | ||
| GMP-BioFcR-ag-031-1 | Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi Size:100mg | 258000 | ||
| GMP-BioFcR-ag-031-2 | Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi, Biotinylated Size:1mg | 6990 | ||
| GMP-BioFcR-ag-031-2 | Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi, Biotinylated Size:10mg | 43790 | ||
| GMP-BioFcR-ag-031-2 | Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi, Biotinylated Size:100mg | 293000 | ||
| GMP-BioFcR-ag-031 | Size≥100mg | Inquiry | ||
| Shipping Cost: | 760.00 | |||
| Total: | ||||
Description
| Products Name | GMP-BioFcR-ag-031-1: Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi GMP-BioFcR-ag-031-2: Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi, Biotinylated |
| Products Description | Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi (Biotinylated) is used to measure the affinity of antibodies for it. The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of therapeutic antibodies. GeneMedi provides Human Neonatal Fc receptor (FcRn) Heterodimer His+Avi (Biotinylated). The receptor has been classified based on its affinity for IgG1, IgG2, IgG3, IgG4 . The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response. |
| Isotype | Neonatal Fc receptor (FcRn) |
| Receptor name | Neonatal Fc receptor (FcRn) Heterodimer |
| Species | Human |
| Principal antibody ligand | IgG1, IgG2, IgG3, IgG4 |
| Major role | Transport/ recycling |
| Effect following binding to antibody | Transfers IgG from a mother to fetus through the placenta, Transfers IgG from a mother to infant in milk, Protects IgG from degradation |
| WT/Mutation | WT |
| Mutant variants functions vs WT | N/A |
| Fc Modifications or Mutations (Reduced effector function) |
|
| Fc Modifications or Mutations (Enhanced effector function) |
IgG1/IgA2 (ADCC) |
| Application | Antibody Fc&Fc Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay) |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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