Products
Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi (Biotinylated) for antibody Fc&Fc
Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay)
Cat No.: GMP-BioFcR-ag-029
Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it.
The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of
therapeutic antibodies.
GeneMedi provides Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi (Biotinylated)
The receptor has been classified based on its affinity for IgG1, IgG3, IgG4. The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.
Order information
GeneMedi provides two kinds of Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) (GMP-BioFcR-ag-029), GMP-BioFcR-ag-029-1 is with the tag His and Avi, GMP-BioFcR-ag-029-2 is Biotinylated and also with the tag His and Avi.
| Catalog No. | Description | Price (In USD) |
Qty (Quantity) | Sum(In USD) |
|---|---|---|---|---|
| GMP-BioFcR-ag-029-1 | Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi Size:1mg | 5990 | ||
| GMP-BioFcR-ag-029-1 | Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi Size:10mg | 38790 | ||
| GMP-BioFcR-ag-029-1 | Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi Size:100mg | 258000 | ||
| GMP-BioFcR-ag-029-2 | Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi, Biotinylated Size:1mg | 6990 | ||
| GMP-BioFcR-ag-029-2 | Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi, Biotinylated Size:10mg | 43790 | ||
| GMP-BioFcR-ag-029-2 | Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi, Biotinylated Size:100mg | 293000 | ||
| GMP-BioFcR-ag-029 | Size≥100mg | Inquiry | ||
| Shipping Cost: | 760.00 | |||
| Total: | ||||
Description
| Products Name | GMP-BioFcR-ag-029-1: Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi GMP-BioFcR-ag-029-2: Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi, Biotinylated |
| Products Description | Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it. The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of therapeutic antibodies. GeneMedi provides Cynomolgus/ Rhesus macaque Neonatal Fc receptor (FcRn) His+Avi (Biotinylated). The receptor has been classified based on its affinity for IgG1, IgG2, IgG3, IgG4 . The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response. |
| Isotype | Neonatal Fc receptor (FcRn) |
| Receptor name | Neonatal Fc receptor (FcRn) |
| Species | Cynomolgus/ Rhesus macaque |
| Principal antibody ligand | IgG1, IgG2, IgG3, IgG4 |
| Major role | Transport/ recycling |
| Effect following binding to antibody | Transfers IgG from a mother to fetus through the placenta, Transfers IgG from a mother to infant in milk, Protects IgG from degradation |
| WT/Mutation | WT |
| Mutant variants functions vs WT | N/A |
| Fc Modifications or Mutations (Reduced effector function) |
|
| Fc Modifications or Mutations (Enhanced effector function) |
|
| Application | Antibody Fc&Fc Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay) |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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