Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi (Biotinylated) for antibody Fc&Fc
Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay)  

Cat No.: GMP-BioFcR-ag-022

Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it.

The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of
therapeutic antibodies.

GeneMedi provides Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi (Biotinylated)
The receptor has been classified based on its affinity for IgG1, IgG3, IgG4. The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.


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GeneMedi provides two kinds of Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158)(GMP-BioFcR-ag-022), GMP-BioFcR-ag-022-1 is with the tag His and Avi, GMP-BioFcR-ag-022-2 is Biotinylated and also with the tag His and Avi.

Catalog No. Description Price
(In USD)		 Qty (Quantity) Sum(In USD)
GMP-BioFcR-ag-022-1 Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi    Size:1mg 5990
GMP-BioFcR-ag-022-1 Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi    Size:10mg 38790
GMP-BioFcR-ag-022-1 Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi     Size:100mg 258000
GMP-BioFcR-ag-022-2 Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi, Biotinylated    Size:1mg 6990
GMP-BioFcR-ag-022-2 Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi, Biotinylated    Size:10mg 43790
GMP-BioFcR-ag-022-2 Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi, Biotinylated    Size:100mg 293000
GMP-BioFcR-ag-022 Size≥100mg Inquiry
Shipping Cost: 760.00
Total:

For more than 100mg, click here for inquiry. >>


Description

Products Name GMP-BioFcR-ag-022-1: Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi
GMP-BioFcR-ag-022-2: Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi, Biotinylated
Products Description Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi (Biotinylated) is used to measure the affinity of antibodies for it. The Fc receptor binding assay (Competitive ELISA immunoassay, SRP assay or BLI assay) plays a vital role in the development of therapeutic antibodies. GeneMedi provides Human Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158) His+Avi (Biotinylated). The receptor has been classified based on its affinity for IgG1, IgG2, IgG3, IgG4 . The Fc receptor is expressed on many immune cells and binds to the specific immunoglobulin, then modulating the immune response.
Isotype Fc gamma receptor IIIA (FcγRIIIA, CD16a)
Receptor name Fc gamma receptor IIIA (FcγRIIIA, CD16a, V158)
Species Human
Principal antibody ligand IgG1, IgG2, IgG3, IgG4
Major role Activation
Effect following binding to antibody ADCC, ADCP
WT/Mutation Mutation
Mutant variants functions vs WT increased affinity to IgG1/3/4
Fc Modifications or Mutations 
(Reduced effector function) 		LE (ADCC),LALA(ADCC, ADCP,),LALA-PG (ADCP),TM,DA (ADCC, ADCP),GRLR (ADCC), IgG2/G4, IgG2m4 (ADCC, ADCP), Glu233Pro, IgG2σ (ADCC, ADCP), IgG1σ(ADCC),Asn297Ala or Gly or Gln (ADCC, ADCP), IgG4 PAA (ADCC)
Fc Modifications or Mutations 
(Enhanced effector function) 		IgG1/IgA2 (ADCC), AAA (ADCC), DLE (ADCC, ADCP), DE (ADCC, ADCP), GASDALIE (ADCC), DAE (ADCC, ADCP), YWA (ADCC), variant 18 (ADCC), Multimeric IgG, Biantennary glycan at N297 (ADCC), Afucosylated glycan at N297 (ADCC)
Application Antibody Fc&Fc Receptor binding affinity assay (Competitive ELISA immunoassay, SRP assay or BLI assay)  
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.